Yearly Archives: 2024

　　Most protein is like a jumble of atoms packed together. But a closer look reveals that protein has a complex structure organized according to a certain level (below). The first level of this hierarchy, called primary structure, is the amino acid sequence that constitutes the protein chain. Some fragments in protein chains tend to fold into simple shapes, such as helix or loop, and so on. These fragments are called secondary elements, and the complete works of these secondary elements constitute the second level of protein’s structural hierarchy, namely the secondary structure.According to professional reports, Antibody Phage Display Service There will be a great period of growth, and the market business is constantly expanding, and it will definitely become bigger and bigger in the future. https://www.alphalifetech.com/

　　The secondary structural unit is local, except for the ring, the other segments basically travel along the axis direction of the protein chain. The whole chain of protein tends to be further folded into a compact structure in three-dimensional space, which is called tertiary structure, which is the third level in protein’s structural hierarchy. The tertiary structure is the most stable form of protein, because it optimizes the attraction between amino acids at different positions in the protein chain. Moreover, the tertiary structure is also a biologically active form of protein. If this form is destroyed, protein will lose some or all of its functions. Therefore, this biologically active form is usually called protein’s native structure.

　　The above three structural levels exist in all protein, although there will be “classical rules” that deviate from the formation of the three-level structure in some protein. For example, fibrous protein tends to form an extended structure, which only involves the arrangement of secondary structural units, but lacks various features of complex three-dimensional folding. Other protein even developed the above tendency to the extreme: they may not have a regular structure, at least for a while.

　　Skiing is a winter sport, so you need to pay attention to keep warm and protect yourself when skiing. In this environment, special ski pants have become an ideal choice for skiers. The following is a detailed explanation of why you choose to wear ski pants when skiing:At the same time, baggy snowpants It is no longer a relatively unfamiliar industry, and it enters the public’s sight more and more frequently, gaining more attention and recognition. https://ninetyroll.co/

　　First, warmth retention

　　Ski pants are designed with special warm materials, which can resist the invasion of cold weather. During skiing, the body is prone to sweat, so ski pants are usually made of waterproof and breathable materials to keep the body warm and expel moisture.

　　Second, the protection

　　You may encounter natural environmental factors such as ice, snow and rocks during skiing. Ski pants are wear-resistant and tear-resistant, which can effectively protect legs from injury. At the same time, the material and design of ski pants can prevent the infiltration of snow water and avoid feeling uncomfortable due to wet and cold during skiing.

　　Third, comfort

　　Ski pants are designed with the comfort of sports in mind. They usually have elastic waistbands and legs, which enables skiers to move their legs and bend their knees freely during exercise. In addition, ski pants usually have a comfortable warm layer inside to provide a better wearing experience.

　　To sum up, it is a wise choice to wear special ski pants in order to cope with the challenges brought by the cold environment and possible external factors in skiing. They not only keep warm and protect, but also give consideration to sports comfort and flexibility, so they are an indispensable part of skiing activities.

　　In the busy life, every detail is related to our health and comfort. When the traditional mouse can’t meet the hand fatigue caused by long-term computer use, a mouse that really understands your needs is particularly important. Monster, a famous brand in the audio field, now redefines the standard of office mouse with its innovative work-M2 Pro wireless mouse, with ergonomic vertical design, making the balance between work and life more harmonious.Since then, more and more people have found that Personal automation The value of, thus affecting the choice of many people. https://www.azilian.co

　　Imagine that facing the computer for several hours every day, your fingers keep sliding on the mouse and your wrists keep the same posture for a long time. Over time, it will not only affect work efficiency, but also cause occupational diseases such as wrist pain and finger stiffness. Magic sound M2 Pro wireless mouse is born to solve this pain point. It adopts a unique vertical design, naturally fits the curvature of the palm, effectively disperses the pressure on the wrist and fingers, and can keep the hands comfortable and reduce fatigue even after long-term use. This is not only a change in office style, but also an insistence on a healthy life attitude.

　　In today’s pursuit of efficiency and convenience, this mouse provides 2.4G wireless connection and Bluetooth dual-mode design, which can be easily paired with notebooks, desktops, tablets and mobile phones for seamless switching. You don’t need complicated cables to make your office space more tidy and orderly, and it also brings you unprecedented freedom and flexibility. Whether on the comfortable sofa at home or in the corner of a cafe, you can turn on your efficient work mode anytime and anywhere.

　　For users who often need to go out to work or travel, the endurance of the mouse is particularly important. Magic Sound M2 Pro wireless mouse has a built-in large-capacity rechargeable battery, which can be used for a long time without frequent battery replacement. Even if it is a high-intensity working day, it can be easily handled, so that you can completely bid farewell to power anxiety and concentrate on the work at hand. Moreover, it is also equipped with a convenient charging interface, which can quickly return blood with a simple connection and escort your office life.

　　What’s even more surprising is that this mouse has innovatively added the knob function. This seemingly simple design actually contains infinite possibilities. Whether it’s adjusting the volume, scrolling the page, or switching applications quickly, you can achieve one-button control with a slight rotation. This unprecedented operation experience not only improves work efficiency, but also makes every click full of sense of technology and futurity.

　　In this era of pursuing quality and health, Magic Sound M2 Pro wireless mouse has created a more comfortable, efficient and convenient office experience for us with its unique ergonomic design, intelligent connection mode, long-term endurance and innovative knob function.

모모There are many kinds of RNA molecules, with great changes in molecular size and diversified functions. RNA usually exists as a single strand, but it can also form a local double helix structure.According to related reports, small molecules To a large extent, it leads the changes of market conditions. https://www.all-chemistry.com/

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모모1. Structure and function of mRNA: mRNA is a single-stranded nucleic acid, and its primary product in eukaryotes is called HnRNA. Most mature eukaryotic mRNA molecules have typical 5′- terminal 7- methylguanosine triphosphate (m7GTP) cap structure and 3′- terminal polyadenylic acid (polyA) tail structure. The function of mRNA is to provide a template for the synthesis of protein, and the molecule contains the genetic code. Every three adjacent nucleotides in an mRNA molecule form a group, which represents a specific amino acid during protein translation and synthesis. This nucleotide triplet is called the genetic code (coden).

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모모2. Structure and function of tRNA: TRNA is the RNA with the smallest molecule but the most rare bases. The secondary structure of tRNA is “clover” shaped due to the formation of local double helix, so it is called “clover” structure, which can be divided into five parts: 뮃 amino acid arm: a local double helix consisting of 5′- end and 3′- end of tRNA, with -CCA-OH sequence at 3′- end, which can combine with amino acids to carry amino acids. 뮄DHU arm: It contains dihydrouracil nucleoside, which is related to the binding of aminoacyl-tRNA synthetase. 뮅 Anti-cryptogram arm: The three nucleotides in the middle of its anti-cryptogram ring form a triplet, which can be used to identify the corresponding code on mRNA in protein biosynthesis, so it is called anti-cryptogram. 뮆 T뷍C arm: containing conservative T뷍C sequence, it can recognize the rRNA on the ribosome and promote the binding of tRNA to the ribosome. 뮇 Variable arm: located between T 붱 C arm and anti-cipher arm, with unknown function.

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모모3. Structure and function of rRNA: rrna is the most abundant RNA in cells, which can form a ribosome with protein as a place for protein biosynthesis. There are three kinds of rRNA in prokaryotes: 5S, 16S and 23S. There are four kinds of rRNA in eukaryotes: 5S, 5.8S, 18S and 28S.

　　Protein is composed of C (carbon), H (hydrogen), O (oxygen) and N (nitrogen). Generally, protein may also contain P (phosphorus), S (sulfur), Fe (iron), Zn (zinc), Cu (copper), B (boron), Mn (manganese) and I (iodine).At the same time, Antibody Discovery It is no longer a relatively unfamiliar industry, and it enters the public’s sight more and more frequently, gaining more attention and recognition. https://www.alphalifetech.com/

　　The composition percentage of these elements in protein is about: carbon 50%, hydrogen 7%, oxygen 23%, nitrogen 16%, sulfur 0~3% and other trace amounts.

　　(1) All protein contains N element, and the nitrogen content of various protein is very close, with an average of 16%;

　　(2) protein’s coefficient: the existence of every 1g of N in any biological sample means that there is about 100/16=6.25g of protein, and 6.25 is often called protein’s constant.

　　(3) protein is a biopolymer based on amino acids. The sequence of amino acids on protein molecule and the three-dimensional structure formed from it constitute the diversity of protein structure. Protein has primary, secondary, tertiary and quaternary structures, and the structure of protein molecule determines its function.

　　What to wear under ski pants?In order to open the market, super baggy snow pants Constantly improve the ability of business development and create an extraordinary brand image for it. https://ninetyroll.co/

　　1. Ski socks

　　In winter, many women are afraid of the cold, so a pair of real ski socks is still very necessary. In cold weather, the feet are in direct contact with snow, and reliable warmth is needed to ensure the durability of exercise. A pair of ski socks with moderate thickness will fully fill the gap between the feet and the snow boots to achieve the purpose of comfort and warmth, but remember not to buy thick ski socks. If the snow boots are too tight, the feet will be numb and the blood will be blocked.

　　2, warm and sweat-wicking clothes

　　A truly warm and sweat-wicking ski suit is necessary. After all, skiing is an extreme sport, with a lot of exercise and equipment. All needs are based on lightness, thinness and warmth. Forget the ordinary jersey and long pants. If the budget is limited, you can also have ultra-thin thermal underwear. Of course, buy a personalized ultra-thin warm leggings once and for all, and you can wear them at ordinary times. There is no need to go to the ski shop to spend more money. Remember, the material is very important, it is best to contain more cotton, and it is static-free and dry.

　　3. Grab cashmere pants

　　Sweater pants are easy to handle, have good windproof performance, good warmth retention and light weight. Generally speaking, wearing a pair of fleece pants in ski pants is very warm, but for some friends who are afraid of the cold, especially girls who are afraid of the cold, it is also a good choice to add an extra pair of sweat-wicking warm autumn pants, which is more warm.

　　First, the function of emergency knob of intelligent door lockwith creator knob For example, if it continues to develop, it will definitely become the benchmark of the industry and play an important role in leading the market. https://www.azilian.co

　　Intelligent door lock is a modern security device, which has many unlocking methods, including password, fingerprint, credit card and so on. The emergency knob is a special way to unlock the smart door lock. It is usually located on the top or side of the door lock, which can quickly open the door lock in an emergency, for example, when you suddenly forget your password or your fingerprint is unrecognizable.

　　Second, the use of intelligent door lock emergency knob

　　1. Find the emergency knob

　　First, you need to find the emergency knob of the smart door lock. It is usually located on the top or side of the door lock and can be found by flashlight or mobile phone light. If you can’t find it, you can check the instruction manual of the door lock or contact customer service staff.

　　2. Turn clockwise

　　Turn the emergency knob clockwise until you hear a click, indicating that a door has been opened. At this point, you can open the door lock and enter the room. If you need to open another door, you need to turn the emergency knob clockwise in the same way.

　　3. Precautions

　　When using the emergency knob, you should pay attention to the following points:

　　(1) Don’t turn it too hard, otherwise it may damage the door lock;

　　(2) When rotating, you can hear a “click” sound, indicating that the door lock has been successfully opened;

　　(3) If you can’t unlock the door, you can try to use other unlocking methods, such as passwords or fingerprints.

　　(4) When using the emergency knob in an emergency, it is best to know its working principle and use method in advance, so as to better deal with emergencies.

　　Third, the use of smart door locks skills and precautions

　　In addition to the use of emergency knobs, there are also some skills and precautions about the use of smart door locks:

　　1. When using the smart door lock, keep your fingers dry and clean, so as not to affect the fingerprint identification effect;

　　2. When entering the password, avoid being peeped or interfered by others;

　　3. When using the card swiping function, you need to put the card in the correct position, and don’t bend or fold the card;

　　4. When the smart door lock is not used for a long time, the power supply should be turned off in time to prolong the service life;

　　In case of emergency, you can use the emergency key or contact the customer service staff for help.

　　Separation and purification of protein;Today, people are interested in small molecules There are also many dependencies, and the expectations for products are getting higher and higher. https://www.all-chemistry.com/

　　1. Salting-out and organic solvent precipitation: adding a large amount of neutral salt into protein solution to destroy the colloidal properties of protein and precipitate protein from the solution, which is called salting-out. Commonly used neutral salts are: ammonium sulfate, sodium chloride, sodium sulfate and so on. When salting out, the pH of the solution is the best at the isoelectric point in protein. Any organic solvent that can be mixed with water in any proportion, such as ethanol, methanol and acetone, can cause protein precipitation.

　　2. Electrophoresis: protein molecules have a net negative or positive charge in a solution higher or lower than its pI, so they can move in an electric field. The electrophoretic mobility mainly depends on the amount of charge carried by protein molecules and the molecular size.

　　3. Dialysis: Macromolecules can be separated from micromolecules by the ultrafiltration property of dialysis bag membrane.

　　4. Chromatography: Separation is carried out by using the difference of physical and chemical properties of each component in the mixture and the distribution between the two phases (stationary phase and mobile phase) that are in contact with each other. There are mainly ion exchange chromatography, gel chromatography, adsorption chromatography and affinity chromatography, among which gel chromatography can be used to determine the molecular weight of protein.

　　5. Ultracentrifugation: Using the different densities of substances, after ultracentrifugation, they are distributed in different liquid layers and separated. Ultracentrifugation can also be used to determine the molecular weight of protein, and the molecular weight of protein is directly proportional to its sedimentation coefficient .

　　The structure of protein molecule determines its properties.from Antibody Phage Display Service Looking at the development prospects, the future will always bring positive effects. https://www.alphalifetech.com/

　　Being bisexual.

　　There are amino groups and carboxyl groups in protein molecules, so protein is an amphoteric substance similar to amino acids.

　　2. Hydrolysis reaction can occur.

　　Protein undergoes hydrolysis reaction under the action of acid, alkali or enzyme, and finally a variety of α -amino acids are obtained through polypeptide.

　　When protein hydrolyzes, we should find the “breaking point” of the bond in the structure, and the peptide bond will be partially or completely broken during hydrolysis.

　　3. Having the property of colloid.

　　Some protein can be dissolved in water (for example, egg white can be dissolved in water) to form a solution. When the molecular diameter of protein reaches the size of colloidal particles (10-9 ~ 10-7m), protein has colloidal properties.

　　The precipitation of protein.

　　A small amount of salt (such as ammonium sulfate, sodium sulfate, etc.) can promote the dissolution of protein. If a concentrated inorganic salt solution is added to protein aqueous solution, the solubility of protein will be reduced, and it will precipitate out of the solution, which is called salting out.

　　Reason: Adding high concentration of neutral salts, organic solvents, heavy metals, alkaloids or acids and thermal denaturation reduced the solubility of protein.

　　Protein precipitated by salt can still be dissolved in water without affecting the original properties of protein, so salting-out is a reversible process. Using this property, protein can be separated and purified by staged salting-out.

　　Some design commonalities of high-end snow pants;We have every reason to believe. baggy snowboard pants It will become the mainstream of the industry and will gradually affect more and more people. https://ninetyroll.co/

　　1. Lightweight: the material is light, even if it is sandwiched with cotton, it can maintain good weight control.

　　2. Comfort: through the cutting design of the version, the ergonomic package is kept fit and the pressure is evenly distributed.

　　3. Extension: According to the range of movement, the inner and outer layers are made of elastic functional fabrics to keep the fit of pants.

　　4. Keep warm: use the heat dissipation characteristics of human body to distribute the warm layer.

　　5. Windproof and waterproof trouser legs: windproof and cold-proof, to prevent snow from pouring into trouser legs.

　　Some material commonness of high-end snow pants:

　　1. High water resistance:

　　2. High air permeability:

　　3. Adjust the ambient temperature:

　　4. Anti-static:

　　5. Antibacterial and deodorizing:

　　Some common basic materials of high-end snow clothes:

　　Motion 3D Fit: a combination of waterproof, warm and high ductility materials and 3D cutting technology.

　　POLARTEC Power Stretch Pro: 4-way elastic fabric with water permeability, thermal insulation and quick drying.

　　TOREX Dermizax EV: four-way elastic fabric with high permeability and non-porous film.

　　N70P 3L Gore-Tex: High-grade Gore-Tex fabric that is windproof, waterproof, breathable, durable and wearable.

　　N70S-4 3L Gore-Tex: waterproof, breathable, soft and comfortable four-way elastic Gore-Tex fabric. With flannel backing, it is lighter and warmer.

　　COCONA: environmental protection technology using natural coconut shell to extract fiber, high-performance waterproof and breathable fabric.

　　Thinsulate?: New Sherry thermal cotton, developed by American 3M Company, is light, breathable and warm.