Yearly Archives: 2024

　　The supercoiled structure formed by the further spiral of DNA molecules is called the tertiary structure of DNA.Actually, it’s not just this reason, small molecules Its own advantages are also obvious, and it is normal for the market to perform well. https://www.all-chemistry.com/

　　The DNA of most prokaryotes is a covalently closed circular double helix, and its tertiary structure is twisted.

　　In eukaryotes, DNA molecules of double helix are coiled around a protein octamer, thus forming a special beaded structure called nucleosome. Nucleosome structure belongs to the tertiary structure of DNA.

　　Protein is a substance with a certain spatial structure, which is formed by the zigzag folding of polypeptide chains composed of amino acids in the form of dehydration and condensation. However, natural protein molecules are not random loose polypeptide chains. Each natural protein has its own unique spatial structure or three-dimensional structure, which is usually called the conformation of protein, that is, the structure of protein. The sequence of amino acids in protein molecule and the three-dimensional structure formed from it constitute the diversity of protein structure.Even if there are obstacles to moving forward, Antibody Discovery We should also persevere, forge ahead bravely, cut waves in the sea of the market, hang on to Yun Fan and strive for the first place. https://www.alphalifetech.com/

　　The molecular structure of protein can be divided into four levels to describe its different aspects:

　　Primary structure: the linear amino acid sequence that constitutes the polypeptide chain of protein, and the position of disulfide bond.

　　Secondary structure: In the local area of protein molecule, the polypeptide chain is coiled and folded along a certain direction.

　　Tertiary structure: The three-dimensional structure of a protein molecule formed by the arrangement of multiple secondary structural elements in three-dimensional space.

　　Quaternary structure: used to describe protein complex molecules with biological functions formed by the interaction between different polypeptide chains (subunits).

　　In addition to these structural levels, protein can be transformed in several similar structures to exercise its biological functions. For functional structural changes, these tertiary or quaternary structures are usually described by chemical conformations, and the corresponding structural transformations are called conformational changes.

　　In the cold winter, skiing is a very popular outdoor sport. Ski pants are one of the essential equipment in skiing. So, when you wear ski pants, do you need to wear pants inside? This question may vary from person to person, depending on personal preferences and needs.As can be seen from the new data, white snow pants The market influence is also growing, and the product share is also relatively increasing, which has great potential in the future. https://ninetyroll.co/

　　Do you still need to wear pants under ski pants?

　　First of all, let’s know the characteristics of ski pants. Ski pants are mainly characterized by their waterproof, windproof and warm-keeping properties. Generally speaking, the outer layer of ski pants is made of waterproof material, which can prevent the infiltration of snow water and keep warm. The inner layer is usually made of warm-keeping materials such as fluff or wool to increase the warm-keeping effect. Therefore, the ski pants themselves have certain warm-keeping performance.

　　So, why would anyone wear pants under ski pants? There are several possible reasons. First of all, some people may think it is more warm. Especially in high-intensity skiing, the body will emit a lot of heat. If you wear a pair of pants under the ski pants, you can effectively stop the heat loss and keep your body warm. Secondly, for some people who have just started to learn skiing, wearing a pair of trousers can provide extra protection to prevent injuries when they fall. Finally, some people may think that wearing pants under ski pants can provide extra security for habit or psychological reasons.

　　Do you still need to wear pants under ski pants?

　　However, some people do not recommend wearing pants under ski pants. First of all, doing so may add extra weight and burden, which will affect the flexibility and comfort of skiing. Secondly, if you wear pants when you fall, it may cause friction between the skin and the snow, increasing the risk of injury. In addition, for some professional skiers, they may pay more attention to portability and flexibility, so wearing pants under ski pants may become a burden.

　　To sum up, whether it is necessary to wear pants under ski pants depends on personal needs and preferences. If you are a beginner in skiing or think it is necessary to increase warmth, it may be a good choice to wear pants under ski pants. But if you pay more attention to lightness and flexibility, or think that doing so may increase the risk of injury, then you may prefer not to wear pants under ski pants.

　　It should be noted that whether you choose to wear pants under ski pants or not, you should consider the warmth and comfort of the material when purchasing. At the same time, make sure that the pants you choose will not affect your normal sports and activities.

　　Do you still need to wear pants under ski pants?

　　In addition, if you choose to wear pants under ski pants, you should also pay attention to the following points:

　　1. Choose suitable materials: Try to choose lightweight and breathable materials to avoid adding extra weight and burden.

　　2. Pay attention to the right size: make sure that the pants you wear are not too tight or loose to avoid affecting comfort and flexibility.

　　3. Consider waterproof performance: If you plan to do activities in the snow for a long time, you should choose pants with waterproof performance to prevent snow water from penetrating and keep your body dry.

　　4. Keep safe: Although wearing pants under ski pants may increase some protection, you should still pay attention to keep safe and try to avoid unnecessary falls and collisions.

　　In a word, whether to wear pants under ski pants depends on personal preferences and needs. No matter what choice you make, you should consider the warmth and comfort of the material, and ensure that the equipment you choose will not affect your normal sports and activities.

　　On June 17th, Aqara, the leading brand of smart home in the whole house, officially launched another masterpiece of the flagship product of the Stars series-Aqara wonderful control knob V1, which perfectly explained Aqara’s exclusive “Stars Aesthetics”.For the current market situation, Personal automation It has a very advantageous development prospect and an extremely superior ecological environment. https://www.azilian.co

　　Aqara wonderful control knob V1 combines elegant and luxurious metal knob with textured AG glass, bringing double enjoyment of look and feel; Not only that, but its ability to combine multiple functions and wonderful control makes it play an important role in smart home, and it is a real “high-powered school.”

　　Stars aesthetics is good at form.

　　Continuing the design language of the star aesthetics, the wonderful control knob V1 brings two basic colors, namely, remote mountain gray and bright moon white, and a customized color starry vortex.

　　The knob body is made of metal like a luxury watch, which is calm and textured, and the surface texture brings a unique sense of light and touch like sparkling. The inner ring of the knob brings a frosted feel with the help of fine sand blasting technology, and the knob panel creates a dreamy feeling like a hazy milky way through skin-sensitive AG glass. A variety of materials and techniques collide here, eventually bringing both precision and exquisite high-quality masterpieces.

　　Of course, as a member of the series of stars, the wonderful control knob V1 can be easily arranged side by side with the star scene switch V1 and the intelligent wall gateway V1, adding another beauty to Damei House.

　　Intelligent and clever control of the heart

　　The core of the clever control knob V1 lies in “turning”. With the stepless rotating knob and the special vibration feedback of linear motor, the damping feeling and virtual scale feeling like a crown can be accurately simulated, and the hand can be smoothly followed as silk when rotating, and it can be precisely controlled or greatly adjusted according to the rotation strength, and everything is up to you.

　　Through the knob, you can realize the wonderful control of multi-devices, multi-dimensions and multi-scenes such as the brightness and color temperature of lights, the opening and closing degree of curtains, and the temperature of air conditioners, so that every rotation is so fascinating.

　　Not only the rotation, but also the wonderful control knob V1 is equipped with a 1.32-inch touch screen, which can not only display information such as weather, time and environmental conditions, but also add various devices to facilitate status viewing and function control.

　　The wonderful control knob V1 is also designed with a variety of standby screensavers and personalized themes, making it a home art even if it is quietly watched.

　　Combine many talents in one body

　　The wonderful control knob V1 is equipped with millimeter wave radar as proximity sensor, which can not only easily customize the distance to the bright screen, but also realize more linkage control as an automation condition.

　　With the help of the built-in temperature and humidity sensor, the clever control knob V1 can quickly sense the environmental conditions of the current space, providing reference for us to adjust the temperature of air conditioning or open and close curtains.

　　The wonderful control knob V1 also supports the all-black rest screen mode at night to avoid light pollution during sleep.

　　Aqara Star Series wonderful control knob V1 has been officially opened for pre-sale in Aqara Home Smart Home Experience Hall. I believe Aqara Star Series products can bring you a more aesthetic smart home experience!

　　Protein is a complex organic polymer compound composed of α -amino acids combined in a certain order to form a polypeptide chain, and then one or more polypeptide chains are combined in a specific way. Amino acids are the basic units of protein, and they are linked into peptide chains through dehydration and condensation. Each polypeptide chain has twenty to hundreds of amino acid residues (-R); Various amino acid residues are arranged in a certain order.It is strictly required by such a standard, recombinant proteins Only with today’s development scale, can we have the proud momentum to crush our competitors. https://www.alphalifetech.com/

　　the composition characteristics of protein

　　The amino acid sequence of protein is encoded by the corresponding gene. In addition to the 20 basic amino acids encoded by the genetic code, in protein, some amino acid residues can be modified after translation to change their chemical structure, thus activating or regulating protein. Multiple protein can form a stable protein complex together, often by combining together, and fold or spiral to form a certain spatial structure, thus playing a specific function. The organelles of synthetic peptides are ribosomes on rough endoplasmic reticulum in cytoplasm. The difference of protein lies in the variety, number, arrangement order of amino acids and the spatial structure of peptide chains.

　　Protein is composed of C (carbon), H (hydrogen), O (oxygen) and N (nitrogen), and generally protein may also contain P (phosphorus), S (sulfur), Fe (iron), Zn (zinc), Cu (copper), B (boron), Mn (manganese) and I (iodine).

　　The composition percentage of these elements in protein is about: 50% carbon, 7% hydrogen, 23% oxygen, 16% nitrogen, 0-3% sulfur and other trace amounts.

　　All protein contains N element, and the nitrogen content of various protein is very close, with an average of 16%;

　　Every 1g of N in any biological sample means that there is about 100/16=6.25g protein, and 6.25 is often called protein constant.

　　Organic chemistry is an important branch of studying carbon compounds, involving the source, structure, properties and other aspects of organic matter, and providing revelation for the material basis of life phenomena. It plays a key role in medicine, industrial production and other fields, but it still faces challenges such as green synthesis and drug molecular selectivity. Organic chemists are constantly exploring new reaction mechanisms and synthetic methods to promote the development of the discipline.For the current market situation, inhibitors It has a very advantageous development prospect and an extremely superior ecological environment. https://www.all-chemistry.com/

　　Generated by the author through intelligent technology

　　In the vast universe of science, organic chemistry is like a bright star, leading us to explore the mystery of life. As a subject of studying carbon compounds, organic chemistry, with its unique charm, closely links all fields of natural science and reveals the material basis of life phenomena for us. Organic chemistry, an important branch of chemistry, is a subject that studies the source, structure, properties, separation, preparation, application and related theories of organic matter. “Organic matter” here refers to compounds containing carbon elements, such as alcohols, aldehydes, carboxylic acids, etc. It is worth noting that although organic matter mainly comes from organisms, with the development of science and technology, people have been able to synthesize many artificial organic compounds with biological activity, such as drugs, dyes, plastics and so on.

　　The main research contents of organic chemistry include: synthetic chemistry of organic matter; Metal organic chemistry and elemental organic chemistry; Physical and theoretical organic chemistry; Stereochemistry; Bioorganic chemistry; Natural product chemistry; Chemistry of organic materials.

　　The importance of organic chemistry:

　　1. Basis of life: From the origin of life to the growth and development of organisms, carbon always plays a vital role. Through the study of organic chemistry, we know the structure and function of biological macromolecules such as protein, nucleic acid, sugar and lipid, which are the material basis of life.

　　2. Key in the field of medicine: Many drugs and bioactive substances are organic compounds, such as antibiotics, antiviral drugs and hormones. By studying the structure and function of these substances, scientists are constantly discovering new treatments to protect human health.

　　3. The core of industrial production: Organic chemistry plays an important role in industrial production. For example, in the process of petroleum refining, heavy hydrocarbons in petroleum can be converted into light hydrocarbons by the action of catalysts; In the process of plastic synthesis, organic chemical reactions provide a steady stream of power for the plastic industry. Although organic chemistry has made remarkable achievements in many fields, it still faces many challenges.

　　First of all, in environmental protection, how to realize green synthesis and reduce the discharge of harmful waste is an urgent problem for organic chemists.

　　Secondly, in the field of medicine, how to improve the selectivity of drug molecules and reduce side effects is also a difficult problem to be solved urgently. Faced with these challenges, organic chemists are constantly exploring new reaction mechanisms, catalysts and synthetic methods. I believe that in the near future, organic chemistry will bring us more surprises and inject new vitality into the development of human society. Organic chemistry, as a discipline to study the molecular cornerstone of life, plays an important role in natural science. Let’s walk into this wonderful world hand in hand, grow in exploration, break through in innovation, and jointly write a bright future of organic chemistry.

　　Points to pay attention to when choosing snow pants:It is reported that, snowboard pants baggy The data performance is getting better and better, which is of great reference value and is likely to become the vane of the industry. https://ninetyroll.co/

　　1. Don’t just look at the fabric, but also cooperate with the lining, cutting technology and ergonomic design to play the role of the fabric.

　　2. there are many grades of core-tex, but the fabric of the highest grade is not necessarily suitable for all scenes.

　　3. Details will determine the comfort, such as the adjustment mode of the belt, the position of the breathable zipper and the position of the pocket. Different designs should be selected according to different scenes.

　　Conventional tailoring and slim tailoring have different application scenarios and different fabrics, so you should choose the tailoring method according to your own needs.

　　Shanghai Guanxian Optoelectronic Technology Co., Ltd. is honored to announce the launch of a brand-new 1.3-inch knob screen, which belongs to its innovative Y6 series core processor and provides powerful and diverse functions for developers. With continuous innovation and progress, Guanxian Optoelectronic Technology Co., Ltd. has brought unique screen solutions to customers. As a new generation of innovative products, the 1.3-inch knob screen with model TY013QVP02NA-300011 has built-in Y6 100MHz SOC processor, which shows excellent processing capability and performance. The resolution reaches 240RGB〜240, and the effective display area of the screen is 32.40mm, which makes it present clear and vivid images and colors. Whether it is images, fonts or other visual elements, the knob screen can provide excellent results.Under people’s attention Personal automation Finally grow into what people need, born for the market and come for the demand. https://www.azilian.co

　　An introduction to the new knob screen

　　The size of the knob screen is 50.00〜30.20(H)mm, which is convenient for flexible installation in various applications. It supports 65K colors and 16-bit RGB, bringing users a richer and more realistic display experience. In 8MB storage space, customers can use 6MB for data storage. The knob screen supports pictures in. jpg and. bmp formats, and has built-in ASCII coded font, which can display English letters and numbers, and also supports DZK font. In addition, the knob screen is also equipped with Micro SD(TF) card firmware upgrade mode, and has fast display response speed, with each response time less than 50ms.

　　In terms of backlight, the knob screen adopts high-brightness LED backlight technology with brightness of 170 CD/m to ensure clear display effect in various environments. Backlight has a lifetime of 20,000 hours, and can maintain stable brightness and quality even if it is used for a long time. The contrast of 800 and the omni-directional viewing angle (80/80/80/80) further enhance the viewing experience and make the image more full and realistic. The 1.3-inch knob screen of Guanxian Optoelectronics Technology Co., Ltd. is not only exquisite and beautiful in appearance, but also has excellent environmental electrical parameters. Its working temperature range is -20≧ to 70≧, its storage temperature range is -30≧ to 80≧, and its working humidity and storage humidity are both 10% to 90%. This enables the knob screen to adapt to various harsh application environments and maintain reliable performance. In terms of communication interface, the knob screen adopts 3.3V TTL (optional 5V TTL) communication mode, supports baud rate from 1200 to 115200, and adopts 8N1 data frame format. The communication plug-in is 4P HY2.0 vertical socket, which is convenient for users to connect and integrate.

　　Guanxian Optoelectronic Technology Co., Ltd. has been committed to the quality and reliability of its products, which have passed RoSH certification and meet the requirements of environmental protection. We launched this 1.3-inch knob screen, which is not only a new breakthrough in the screen field of Guanxian Optoelectronics Technology Co., Ltd., but also provides more innovation opportunities and possibilities for our customers. Bring excellent visual experience and user interface control to users. The 1.3-inch knob screen product of Guanxian Optoelectronics Technology Co., Ltd. has been officially released. Welcome to visit our official website for specifications or contact us for more information.

　　Amino acid chain is the main and core component in protein, but it is not necessarily the only component. Some protein may include some atoms or small molecules, whose function may be to perform protein function and/or increase its stability. Chemically, these cofactor are diverse, which may be organic molecules or metal elements. Some of them are briefly combined with protein chain, while others are closely combined with protein chain (sometimes even by covalent bonds) and become an integral part of the whole protein. The former is called coenzyme coenzyme, while the latter is called prosthetic group. Most coenzymes are small organic molecules from vitamins. For example, the common coenzymes NADH and FADH2. These two molecules from vitamin B complex, the former from nicotinic acid (vitamin B3) and the latter from riboflavin (vitamin B2), play the role of high-energy electron acceptor/donor in redox reaction.consequently recombinant proteins I also got a lot of attention and wanted to join the ranks. https://www.alphalifetech.com/

　　Some enzymes use several different cofactors, such as Pyruvate dehydrogenase (PDH), which is a key enzyme in the catabolism of sugar. The catabolism of sugar begins with glycolysis, which is a biochemical reaction pathway with 10 steps, transforming one glucose molecule into two pyruvate molecules, and then carrying out the citric acid cycle of tricarboxylic acid, which further decomposes pyruvate and oxidizes it into CO2. Pyruvate dehydrogenase PDH works at the intermediate junction of the above two reaction pathways (namely glycolysis and triacid cycle), and is responsible for activating pyruvate and enabling it to enter the tricarboxylic acid cycle. Specifically, PDH catalyzes the oxidative dearboxylation of pyruvate and forms acetyl coenzyme A (ACoA), which is the activated form of pyruvate. PDH is not a single enzyme but a complex composed of three components, each of which participates in a different step of pyruvate activation and uses different coenzymes. The first component uses thiamine pyrophosphate (TPP), which is a derivative of thiamine (vitamin B1). TPP allows the first component of PDH to be oxidized and decarboxylated at the same time, thus transforming pyruvate into acetyl, and the remaining carbon is discharged as CO2. The importance of TPP will be reflected in its absence. In fact, if people can’t get enough thiamine from food, they will get beriberi, which will damage several major systems of the human body.

　　The second component in PDH uses lipoic acid. It is an auxiliary group covalently bound to PDH. The active part of lipoic acid is a cyclic structure, which contains two covalently bonded sulfur atoms (that is, S-S bonds) (Figure 2.2c). This active part catalyzes the transfer of acetyl to coenzyme coenzyme A(CoA), the third cofactor of PDH. CoA is pantothenic acid, also known as the derivative of calcium pantothenate. The combination of acetyl and pantothenic acid involves the reduction of S-S bond, and its cyclic structure will open and form two sulfhydryl groups (one SH), one of which will bind acetyl. Sulfhydryl group is easy to react chemically, which can be reflected in the fact that sulfhydryl group is easily influenced by arsenic, a toxic derivative of arsenic. To sum up, the formation of acetyl coenzyme A involves the reduction of S-S bond of pantothenic acid cyclic structure. In order to keep PDH active, these two sulfur groups must be re-oxidized to restore the S-S bond.

　　The amino acid sequence analysis of protein polypeptide chain, that is, the determination of protein primary structure, mainly includes the following steps:in fact Chemical Custom synthesis Our related products were once praised by users, which is the best self-affirmation of the products. https://www.all-chemistry.com/

　　1. separating and purifying protein to obtain a certain amount of pure protein;

　　2. Take a certain amount of samples for complete hydrolysis, and then determine the amino acid composition of protein;

　　3. Analyze the N- terminal and C- terminal amino acids of protein;

　　4. Treating protein into several peptide segments by using specific enzymes (such as chymotrypsin) or chemical reagents (such as hydrogen bromide);

　　5. separating and purifying a single peptide segment;

　　The amino acid sequence of each peptide was determined. Edman degradation method is generally used, and phenyl isothiocyanate is used to react, and amino acids are degraded and determined one by one.

　　7. Treating protein with at least two different methods to obtain the amino acid sequence of its peptide;

　　8. Compare the amino acid sequences of two different peptide groups to obtain the complete amino acid sequence of protein molecule.