In the busy life, every detail is related to our health and comfort. When the traditional mouse can’t meet the hand fatigue caused by long-term computer use, a mouse that really understands your needs is particularly important. Monster, a famous brand in the audio field, now redefines the standard of office mouse with its innovative work-M2 Pro wireless mouse, with ergonomic vertical design, making the balance between work and life more harmonious.This is due to smart home knob Its value attribute is relatively large, and it is easy to become the backbone of the industry. https://www.azilian.co

　　Imagine that facing the computer for several hours every day, your fingers keep sliding on the mouse and your wrists keep the same posture for a long time. Over time, it will not only affect work efficiency, but also cause occupational diseases such as wrist pain and finger stiffness. Magic sound M2 Pro wireless mouse is born to solve this pain point. It adopts a unique vertical design, naturally fits the curvature of the palm, effectively disperses the pressure on the wrist and fingers, and can keep the hands comfortable and reduce fatigue even after long-term use. This is not only a change in office style, but also an insistence on a healthy life attitude.

　　In today’s pursuit of efficiency and convenience, this mouse provides 2.4G wireless connection and Bluetooth dual-mode design, which can be easily paired with notebooks, desktops, tablets and mobile phones for seamless switching. You don’t need complicated cables to make your office space more tidy and orderly, and it also brings you unprecedented freedom and flexibility. Whether on the comfortable sofa at home or in the corner of a cafe, you can turn on your efficient work mode anytime and anywhere.

　　For users who often need to go out to work or travel, the endurance of the mouse is particularly important. Magic Sound M2 Pro wireless mouse has a built-in large-capacity rechargeable battery, which can be used for a long time without frequent battery replacement. Even if it is a high-intensity working day, it can be easily handled, so that you can completely bid farewell to power anxiety and concentrate on the work at hand. Moreover, it is also equipped with a convenient charging interface, which can quickly return blood with a simple connection and escort your office life.

　　What’s even more surprising is that this mouse has innovatively added the knob function. This seemingly simple design actually contains infinite possibilities. Whether it’s adjusting the volume, scrolling the page, or switching applications quickly, you can achieve one-button control with a slight rotation. This unprecedented operation experience not only improves work efficiency, but also makes every click full of sense of technology and futurity.

　　In this era of pursuing quality and health, Magic Sound M2 Pro wireless mouse has created a more comfortable, efficient and convenient office experience for us with its unique ergonomic design, intelligent connection mode, long-term endurance and innovative knob function.

　　Some design commonalities of high-end snow pants;In the industry, cargo snow pants Has been a leader in the industry, but later came from behind but never arrogant, low-key to adhere to quality. https://ninetyroll.co/

　　1. Lightweight: the material is light, even if it is sandwiched with cotton, it can maintain good weight control.

　　2. Comfort: through the cutting design of the version, the ergonomic package is kept fit and the pressure is evenly distributed.

　　3. Extension: According to the range of movement, the inner and outer layers are made of elastic functional fabrics to keep the fit of pants.

　　4. Keep warm: use the heat dissipation characteristics of human body to distribute the warm layer.

　　5. Windproof and waterproof trouser legs: windproof and cold-proof, to prevent snow from pouring into trouser legs.

　　Some material commonness of high-end snow pants:

　　1. High water resistance:

　　2. High air permeability:

　　3. Adjust the ambient temperature:

　　4. Anti-static:

　　5. Antibacterial and deodorizing:

　　Some common basic materials of high-end snow clothes:

　　Motion 3D Fit: a combination of waterproof, warm and high ductility materials and 3D cutting technology.

　　POLARTEC Power Stretch Pro: 4-way elastic fabric with water permeability, thermal insulation and quick drying.

　　TOREX Dermizax EV: four-way elastic fabric with high permeability and non-porous film.

　　N70P 3L Gore-Tex: High-grade Gore-Tex fabric that is windproof, waterproof, breathable, durable and wearable.

　　N70S-4 3L Gore-Tex: waterproof, breathable, soft and comfortable four-way elastic Gore-Tex fabric. With flannel backing, it is lighter and warmer.

　　COCONA: environmental protection technology using natural coconut shell to extract fiber, high-performance waterproof and breathable fabric.

　　Thinsulate?: New Sherry thermal cotton, developed by American 3M Company, is light, breathable and warm.

　　I. AnswersTherefore, Azilian lifemotion Only then will more and more pump owners cheer for it and spread the value and function of the brand. https://www.azilian.co

　　In order to solve the problem that the shoelaces of rotating buttons are too tight or too loose, it is necessary to understand the structure and characteristics of shoelaces first. Usually, just gently adjust the knob on the button up or down. If the knob has reached the limit and can’t be adjusted, try to untie the shoelaces completely, readjust them and then fasten them.

　　Second, the analysis shows that

　　Characteristics of rotating button shoelaces

　　Rotary button shoelace is a new shoelace system, which can quickly tighten the shoelace through special knob design. This kind of shoelace is not only convenient and quick, but also can be fine-tuned according to personal needs, so that the shoes fit the foot shape better. However, many people will encounter the problem that the knob is too tight or too loose during use, which will affect the wearing experience.

　　Adjustment method of knob tightness

　　(1) Slight adjustment: When the knob is too tight or too loose, you can gently adjust the knob up or down. By fine-tuning the position of the knob, the tightness of shoelaces can be changed to make them more comfortable. Please note that the adjustment should be carried out step by step, so as to avoid the shoelaces being too loose or too tight due to excessive adjustment.

　　(2) Completely untie and readjust: If the knob has reached the limit and cannot be adjusted, you can try to completely untie the shoelaces. Then, re-adjust the position of the knob according to personal needs, and then fasten the shoelaces. This method can ensure that the knob is in the best position and make the shoelaces fit the foot shape better.

　　matters need attention

　　(1) When adjusting the tightness of the knob, keep the knob dry and clean. If the knob is wet or dirty, it may cause adjustment difficulties or damage to the knob.

　　(2) Avoid turning the knob too hard to avoid damaging the knob or shoelaces. It should be adjusted gently to achieve the best tightness.

　　(3) Regularly check the wear of knobs and shoelaces. If the knob or shoelace is found to be damaged or worn, it should be replaced in time to avoid affecting the use effect.

　　Third, the actual operation steps

　　First, observe the position of the knob. If the knob is too tight or too loose, it needs to be adjusted accordingly.

　　Gently adjust the knob up or down with your fingers. Pay attention to it step by step to avoid over-adjustment.

　　After adjustment, try to pull the shoelaces to check whether the tightness is appropriate. If it is still not suitable, continue to make adjustments.

　　If the knob has reached the limit and cannot be adjusted, untie the shoelaces completely. Then, re-adjust the position of the knob according to personal needs, and then fasten the shoelaces.

　　Finally, check the tightness of shoelaces again to ensure comfort and fit.

　　IV. Summary and Prospect

　　Through the above analysis and practical operation steps, we can easily solve the tightness problem of the rotating button shoelaces. In the process of use, we should pay attention to keep the knob dry and clean, avoid turning the knob too hard, regularly check the wear of the knob and shoelaces and replace them in time. Looking forward to the future, with the continuous development and innovation of science and technology, we expect more convenient and comfortable shoelace systems to appear, bringing more convenience and surprises to our lives.

　　Focus on glycolysis, aerobic oxidation of sugar, pentose phosphate bypass, gluconeogenesis, synthesis of ketone bodies, cholesterol and phospholipids, respiratory chain, oxidative phosphorylation, special amino acid metabolites, one carbon unit metabolism, purine and pyrimidine nucleotide synthesis raw materials and catabolites, and substance metabolism.The data shows that, Chemical Custom synthesis Its development potential should not be underestimated, and it is also the inevitability of its existence. https://www.all-chemistry.com/

　　The chapter on sugar metabolism is the focus of the exam, so we should master it comprehensively. The chemical reaction formula of sugar metabolism is complicated, and the focus of the annual examination is basically on the reaction site, key enzymes and regulation, energy production and the relationship between important substances. Glycolysis, gluconeogenesis and aerobic oxidation of sugar are all contents that must be familiar with. The synthesis of ketone bodies and cholesterol in lipid metabolism, pay attention to the difference between them. Ketones are synthesized in the liver and utilized outside the liver, while fats are synthesized in the liver and stored outside the liver. Fat synthesis, ketone body synthesis and cholesterol synthesis are the raw materials of acetyl-CoA synthesis. Synthesis and decomposition of fatty acid, the main material of fatty acid synthesis is acetyl CoA; Under the condition of sufficient oxygen supply, fatty acid is decomposed into CO2 and water in the body, releasing a lot of energy, which is the main form of fatty acid catabolism in the body. Phospholipid synthesis. Differentiation of several blood lipids.

　　Composition of respiratory chain and influencing factors of oxidative phosphorylation. Urea synthesis-ornithine cycle. One carbon unit’s metabolism is often tested, but it is easy to remember as long as you grasp the core content. It comes from one carbon unit-Sisegan, and is transported by one carbon unit-tetrahydrofolate. One carbon unit plays an important role in nucleic acid biosynthesis as a raw material for purine and pyrimidine synthesis, connecting amino acids and nucleotides. Comparison of nucleotide synthesis and decomposition between purine and pyrimidine. The changes in this year’s syllabus are: the deamination of amino acids (oxidative deamination, transamination and combined deamination) is changed to the general metabolism of amino acids (degradation of protein in vivo, oxidative deamination, transamination and combined deamination), which should be reviewed.

　　Protein is the “building material” of organisms and cells, such as protein in muscles, and human hair and nails are all made of protein.Hope for the future Antibody Phage Display Service It can achieve rapid and stable development and serve social development and people’s needs well. https://www.alphalifetech.com/

　　Catalytic function:

　　The chemical essence of most enzymes in organisms is protein. In our daily life, we also use enzyme-added washing powder, which can effectively remove stains.

　　Immune function:

　　In our present environment, there are bacteria and viruses everywhere, and our body will not get sick every three days with an immune system, and immune proteins, such as antibodies, play a key role in this.

　　Transport function:

　　Protein with transport function can be divided into two categories, one is familiar to us-hemoglobin in red blood cells, which is used to transport oxygen; The other is the carrier protein on biofilm, which is used to transport amino acids, glucose and other substances.

　　Adjustment function:

　　Some protein can transmit information and regulate the life activities of the body. Such as insulin, which regulates glucose metabolism.

　　In the cold winter, skiing is a very popular outdoor sport. Ski pants are one of the essential equipment in skiing. So, when you wear ski pants, do you need to wear pants inside? This question may vary from person to person, depending on personal preferences and needs.In the long run, grey baggy snow pants The value will be higher and higher, and there will be a great leap in essence. https://ninetyroll.co/

　　Do you still need to wear pants under ski pants?

　　First of all, let’s know the characteristics of ski pants. Ski pants are mainly characterized by their waterproof, windproof and warm-keeping properties. Generally speaking, the outer layer of ski pants is made of waterproof material, which can prevent the infiltration of snow water and keep warm. The inner layer is usually made of warm-keeping materials such as fluff or wool to increase the warm-keeping effect. Therefore, the ski pants themselves have certain warm-keeping performance.

　　So, why would anyone wear pants under ski pants? There are several possible reasons. First of all, some people may think it is more warm. Especially in high-intensity skiing, the body will emit a lot of heat. If you wear a pair of pants under the ski pants, you can effectively stop the heat loss and keep your body warm. Secondly, for some people who have just started to learn skiing, wearing a pair of trousers can provide extra protection to prevent injuries when they fall. Finally, some people may think that wearing pants under ski pants can provide extra security for habit or psychological reasons.

　　Do you still need to wear pants under ski pants?

　　However, some people do not recommend wearing pants under ski pants. First of all, doing so may add extra weight and burden, which will affect the flexibility and comfort of skiing. Secondly, if you wear pants when you fall, it may cause friction between the skin and the snow, increasing the risk of injury. In addition, for some professional skiers, they may pay more attention to portability and flexibility, so wearing pants under ski pants may become a burden.

　　To sum up, whether it is necessary to wear pants under ski pants depends on personal needs and preferences. If you are a beginner in skiing or think it is necessary to increase warmth, it may be a good choice to wear pants under ski pants. But if you pay more attention to lightness and flexibility, or think that doing so may increase the risk of injury, then you may prefer not to wear pants under ski pants.

　　It should be noted that whether you choose to wear pants under ski pants or not, you should consider the warmth and comfort of the material when purchasing. At the same time, make sure that the pants you choose will not affect your normal sports and activities.

　　Do you still need to wear pants under ski pants?

　　In addition, if you choose to wear pants under ski pants, you should also pay attention to the following points:

　　1. Choose suitable materials: Try to choose lightweight and breathable materials to avoid adding extra weight and burden.

　　2. Pay attention to the right size: make sure that the pants you wear are not too tight or loose to avoid affecting comfort and flexibility.

　　3. Consider waterproof performance: If you plan to do activities in the snow for a long time, you should choose pants with waterproof performance to prevent snow water from penetrating and keep your body dry.

　　4. Keep safe: Although wearing pants under ski pants may increase some protection, you should still pay attention to keep safe and try to avoid unnecessary falls and collisions.

　　In a word, whether to wear pants under ski pants depends on personal preferences and needs. No matter what choice you make, you should consider the warmth and comfort of the material, and ensure that the equipment you choose will not affect your normal sports and activities.

　　We often talk about future technological trends, but sometimes we have to admit that in the pursuit of more efficient digital world, there are also many classic solutions with great times, which are gradually being eliminated by rapidly changing emerging technologies.At the same time, smart home knob It is no longer a relatively unfamiliar industry, and it enters the public’s sight more and more frequently, gaining more attention and recognition. https://www.azilian.co

　　To this end, Ai Faner will launch a series of articles around the theme of “Good Design Abandoned by the Times” to discuss the exquisite structural designs that have accompanied us day and night, their past, present and future stories. This is the first article.

　　The knob has been half buried in the grave, which was ten years ago, and no one will believe it.

　　You may remember that when you were a child, almost every household had an old-fashioned radio, and the silver cylindrical knob was evenly engraved with scales. One of the joys of childhood is to lie on one side and fiddle with the knob. The sizzling sound of electricity in the radio, the babbling sound of human voice and music appear alternately with the rotation, as if the sound waves with emotions have been transmitted alternately and endlessly.

　　Maybe not on the radio, but I’m sure you’ve felt something similar.

　　The knob is not an invention that changes the world, but it can do what keys can’t.

　　As a mechanical structure, it is impossible to test which equipment the knob first appeared on. Maybe it was a telegraph in the last century? Or some oscillograph? It may also be the later radio or TV. Like many buttons, it was naturally born on electronic equipment, and then gradually became popular, becoming a part of the electronic dashboard, and it has been used as a controller all the way to this day.

　　The knob itself is very delicate, which is different from pressing a switch to output only one quantity. The knob may correspond to several quantities or a limited range of “0-10”. For example, the common volume knob will allow the user to make any adjustment within a certain value, and the desired volume can be obtained with a slight turn, which can not be achieved by pressing the up and down buttons all the time.

　　Because of this feature, when you adjust the volume by turning the knob, you don’t look at the scale information carefully (some don’t even have a scale). Maybe you don’t care about the size of the number at all, but you will “find” a just right sound with your ears.

　　A similar experience can also be felt from the desk lamp. We will adjust the brightness through rotation, but in fact we are also relying on our eyes to find the right light source, instead of paying attention to a specific digital scale or color temperature range.

　　If it is a product that really pursues texture, it will also pay attention to the damping feeling of the knob, in order to allow users to adjust to their desired position more accurately through the feel, whether it is a paragraph-like jam or a smooth transformation, it will make people fondle.

　　A typical example is the first batch of Atari game consoles in the 1970s. At that time, the joystick and direction keys were not yet born, and all the controls were handed over to the knobs. Although it can only control two directions, the rotation degree of the knob can output more accurate moving variables than the keys, which is enough to play a simple 2D plane game like PONG.

　　This is the immersive experience brought by the knob, which can make people focus on the information itself. Or, under this continuous control, we will naturally have this intuitive behavior, because our ears and eyes have already responded to the results in advance.

　　But even with such exquisite design, the knob has rarely appeared on mobile phones or computers. Now, let’s not talk about common devices. Smartphones and laptops are basically invisible to us. Even in the era when the touch screen has not become a standard configuration, the knob is not the first choice for most products.

　　But the knob is not completely extinct. You can still see it in some specific places, such as the ECG monitor in the hospital or the mixer in the school broadcasting room. There are still controllers of various sizes on such professional instruments. Some consumer electronics products also recognize the intuitive and easy-to-use characteristics behind the knob, so it also exists as an auxiliary interaction scheme.

　　If those digital and graphical controllers pursue unity and high efficiency, then the knob and so on are preserved, which may be our original unconscious cognition of this operation mode.

　　Good design should dance with the times

　　It is quite logical that Digital Crown will appear on Apple Watch. According to Jony Ive, the chief designer of Apple at that time, he hoped to create a “strange familiarity”-both the meaning of crown in traditional watches and the form of auxiliary interaction of smart watches.

　　I still remember a very clear detail. When setting the alarm clock interface through Apple Watch, you slowly push the Digital Crown knob, and the numbers will jump one by one. Once the speed of pushing is fast, the numbers will change rapidly with this frequency, which is exactly the same as the sense of control brought by the crown of the traditional watch, and this knob can be operated with only one finger.

　　At its root, Apple Watch is not like a smart phone. Its screen size is only about 1.5 inches. Two fingers can cover the whole screen, and it is impossible to control it accurately.

　　In order to avoid the problem of visual occlusion, the original virtual crown scheme was directly abandoned, and the Digital Crown appeared in a physical form. At the same time, there was a pressure-sensitive touch control developed based on Taptic Engine, which also continued to the later iPhone.

　　The Dial input device on Surface Studio may be regarded as the most creative attempt in the Microsoft Surface series. Anyone who picks up this huge cylinder will basically understand how to use it as a part of the “button” and as a “knob”. Although this is not an interactive scheme for mass consumers, I believe that most people will like this simple, direct and attractive design as long as they get started.

　　The amino acid sequence analysis of protein polypeptide chain, that is, the determination of protein primary structure, mainly includes the following steps:precisely because inhibitors The rapid development of, so also brought new opportunities to the industry. https://www.all-chemistry.com/

　　1. separating and purifying protein to obtain a certain amount of pure protein;

　　2. Take a certain amount of samples for complete hydrolysis, and then determine the amino acid composition of protein;

　　3. Analyze the N- terminal and C- terminal amino acids of protein;

　　4. Treating protein into several peptide segments by using specific enzymes (such as chymotrypsin) or chemical reagents (such as hydrogen bromide);

　　5. separating and purifying a single peptide segment;

　　The amino acid sequence of each peptide was determined. Edman degradation method is generally used, and phenyl isothiocyanate is used to react, and amino acids are degraded and determined one by one.

　　7. Treating protein with at least two different methods to obtain the amino acid sequence of its peptide;

　　8. Compare the amino acid sequences of two different peptide groups to obtain the complete amino acid sequence of protein molecule.

　　Amino acid chain is the main and core component in protein, but it is not necessarily the only component. Some protein may include some atoms or small molecules, whose function may be to perform protein function and/or increase its stability. Chemically, these cofactor are diverse, which may be organic molecules or metal elements. Some of them are briefly combined with protein chain, while others are closely combined with protein chain (sometimes even by covalent bonds) and become an integral part of the whole protein. The former is called coenzyme coenzyme, while the latter is called prosthetic group. Most coenzymes are small organic molecules from vitamins. For example, the common coenzymes NADH and FADH2. These two molecules from vitamin B complex, the former from nicotinic acid (vitamin B3) and the latter from riboflavin (vitamin B2), play the role of high-energy electron acceptor/donor in redox reaction.beyond doubt Antibody Discovery It will definitely lead the development direction of the whole industry and let its light bloom in this field. https://www.alphalifetech.com/

　　Some enzymes use several different cofactors, such as Pyruvate dehydrogenase (PDH), which is a key enzyme in the catabolism of sugar. The catabolism of sugar begins with glycolysis, which is a biochemical reaction pathway with 10 steps, transforming one glucose molecule into two pyruvate molecules, and then carrying out the citric acid cycle of tricarboxylic acid, which further decomposes pyruvate and oxidizes it into CO2. Pyruvate dehydrogenase PDH works at the intermediate junction of the above two reaction pathways (namely glycolysis and triacid cycle), and is responsible for activating pyruvate and enabling it to enter the tricarboxylic acid cycle. Specifically, PDH catalyzes the oxidative dearboxylation of pyruvate and forms acetyl coenzyme A (ACoA), which is the activated form of pyruvate. PDH is not a single enzyme but a complex composed of three components, each of which participates in a different step of pyruvate activation and uses different coenzymes. The first component uses thiamine pyrophosphate (TPP), which is a derivative of thiamine (vitamin B1). TPP allows the first component of PDH to be oxidized and decarboxylated at the same time, thus transforming pyruvate into acetyl, and the remaining carbon is discharged as CO2. The importance of TPP will be reflected in its absence. In fact, if people can’t get enough thiamine from food, they will get beriberi, which will damage several major systems of the human body.

　　The second component in PDH uses lipoic acid. It is an auxiliary group covalently bound to PDH. The active part of lipoic acid is a cyclic structure, which contains two covalently bonded sulfur atoms (that is, S-S bonds) (Figure 2.2c). This active part catalyzes the transfer of acetyl to coenzyme coenzyme A(CoA), the third cofactor of PDH. CoA is pantothenic acid, also known as the derivative of calcium pantothenate. The combination of acetyl and pantothenic acid involves the reduction of S-S bond, and its cyclic structure will open and form two sulfhydryl groups (one SH), one of which will bind acetyl. Sulfhydryl group is easy to react chemically, which can be reflected in the fact that sulfhydryl group is easily influenced by arsenic, a toxic derivative of arsenic. To sum up, the formation of acetyl coenzyme A involves the reduction of S-S bond of pantothenic acid cyclic structure. In order to keep PDH active, these two sulfur groups must be re-oxidized to restore the S-S bond.

　　How to wash ski pants?from ninetyroll snowpants Looking at the development prospects, the future will always bring positive effects. https://ninetyroll.co/

　　1. Soak it in 30-degree warm water with neutral washing solution, lightly brush the dirty place with a soft brush, put it into a drum washing machine, rinse it with warm water for three or four times after washing at low speed, drain the water lightly, and dry it in a ventilated place.

　　2. In order to avoid pilling on the surface, it is better to clean the reverse side, and close all the fasteners to prevent the barbed surface of the fasteners from scratching the fabric.

　　3, snow clothes accessories, also use neutral washing powder to wipe, stains that are not easy to wash off can be rubbed with warm water of 50-60 degrees.

　　4. Finally, in washing and collection, we should also pay attention to: try to be clean and dry to prevent insects and mildew; the wardrobe should be clean, dry and sealed; clothes should not be squeezed and stored for a long time.