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According to a report by the Wall Street Journal on July 15, people familiar with the matter revealed that business tycoon Elon Musk said he plans to donate about $45 million a month to a new super political action committee that supports former President Trump.

Reported that other supporters of the newly established U.S. Political Action Committee include Palantil technology co-founder Joe Lonsdale, the Winkleworth brothers, former U.S. ambassador to Canada Kelly Craft and her husband Joe Craft.

According to a person familiar with the matter, the political action committee, established in June, is mainly responsible for registering voters, persuading voters to vote as soon as possible, and requiring ballots to be mailed in swing states.

Musk is currently the richest man in the world, with an estimated wealth of more than US$250 billion. But the amount of donations he said was also staggering.

According to reports, the largest known campaign donation in 2024 to date is $50 million, donated by the great-grandson of banker Thomas Mellon to support one of Trump’s super political action committees.

According to documents submitted on the 15th, as of June 30, the U.S. Political Action Committee received a total of US$8.75 million in donations. A person familiar with the matter said Musk said he plans to start donating in July.

The report also said that Musk officially expressed support for Trump shortly after the shooting. He posted on social platform X: The last time a presidential candidate encountered such a severe test was Theodore Roosevelt. (Compiled by Pan Xiaoyan)

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Around 20:00 local time on the 22nd, a shooting occurred in a concert hall on the outskirts of Moscow, Russia. The latest situation:

Terrorist attacks on concert halls have killed more than 60 people

The number of victims may increase.

A shooting occurred in a concert hall on the outskirts of the Russian capital Moscow on March 22. The Russian Foreign Ministry said on the 22nd that the shooting that took place in the concert hall of Krokus on the outskirts of Moscow that day was a terrorist attack. The investigation Commission of the Russian Federation said it would conduct a criminal investigation into the shooting in the concert hall in accordance with the provisions of terrorist acts.

The investigation Commission of the Russian Federation says more than 60 people have been killed in the attack. The number of victims is likely to increase.

According to Russian local media reports, law enforcement officials are searching for a white car that may have been used by the perpetrators of the concert hall shooting. It is reported that after the attack, four of them ran out of the concert hall, changed into prepared clothes and fled the scene.

Putin gives instructions

According to RIA Novosti news agency reported on the 22nd local time, Russian President Vladimir Peskov said that Russian President Vladimir Putin has made all necessary instructions on the attack on the concert hall on the outskirts of Moscow.

Peskov also said that within minutes of the incident, Putin knew about the terrorist attack and continued to keep abreast of the latest information.

The smoke once affected the rescue.

All-round enhancement of urban vigilance

At 3: 00 a.m. local time on the 23rd, Wang Bin, a reporter from the Central Radio and Television General Station, saw in the parking lot of the concert hall where the shooting occurred in Moscow, Russia, that rescue vehicles at the scene had been reduced, and the possibility of a further rise in the death toll could not be ruled out.

, the length is 01:52.

Earlier, members of the Russian National Guard were unable to stay for a long time during the search and rescue process in the concert hall due to the influence of thick smoke.

After the terrorist attacks, the Russian Ministry of Transport announced that security checks at airports and railway stations will be strengthened to remind passengers going to airports or railway stations to travel ahead of time. Russia’s Vnukovo airport, which is relatively close to the site of the incident, announced that it had stepped up security. The Ministry of Culture of the Russian Federation announced that all public and recreational activities of federal cultural institutions have been cancelled in the next few days. Moscow Mayor Sobyanin announced the evening of 22 local time, cancel all cultural, sports and other public activities held in Moscow over the weekend.

Survivors tell stories of thrilling moments

Some survivors of the attack told the media about the scary moments of the attack.

Several heavily armed attackers shot at the crowd and set fire to the building where the concert hall is located. According to RIA Novosti, the roof of the building collapsed. Earlier, trapped people were waiting for rescue on the roof. Russian rescue workers evacuated about 100 people from the basement of the burning building.

Russian Foreign Ministry spokesman Zakharovaa said the international community must condemn this inhuman crime. Zakharovaa also said that if the United States has and currently has reliable information about the attack, it should be handed over to Russia immediately. The US Embassy in Russia issued a notice on it on the 7th of this month that Russia will face a terrorist threat within the next 48 hours, and that extremists plan to attack large crowd gathering places in Moscow, including concert halls.

The Security Council issued a statement

Strongly condemns the terrorist attack on the Russian concert hall

On March 22, local time, the United Nations Security Council issued a statement strongly condemning the terrorist attack at a concert hall on the outskirts of Moscow, Russia.

The statement said it was a heinous cowardly terrorist attack. Members of the Council expressed their deepest sympathy and condolences to the families of the victims and the Russian people and wished the injured a full recovery as soon as possible.

Members of the Council reaffirmed that terrorism in all its forms and manifestations is one of the most serious threats to international peace and security.

The statement stressed that the perpetrators, organizers, financiers and supporters of these reprehensible terrorist acts should be held accountable and brought to justice. All States are urged to cooperate actively with the Government of the Russian Federation and all other relevant authorities in this regard in accordance with their obligations under international law and relevant Security Council resolutions.

The Council reiterates that any terrorist act is a crime and cannot be excused, regardless of its motive, when, where and by whom it was committed. All States must adopt all means to combat the threat to international peace and security posed by terrorist acts in accordance with their obligations under the Charter of the United Nations and international law.

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Damascus, March 17 (Reporters Ji Ze Cheng Shuaopeng) The United Nations Secretary-General’s Special Envoy for Syria, Pei Kairu, said in the Syrian capital Damascus on the 17th that the current situation in Syria is extremely difficult and faces challenges in security, economic and political process.

After meeting with Syrian Foreign Minister Mekdad that day, Pei Kaiju told the media that Syria’s humanitarian needs are increasing, but aid funds are decreasing.

Regarding the recent escalation of the conflict between the Syrian government and the opposition, Pei Kaiju urged both sides to resolve the crisis politically in a way that gave hope to the Syria people. He also said that the United Nations will continue to work hard to increase aid funds to help Syria meet relevant challenges.

The World Health Organization said on the 16th that the number of people in need of humanitarian assistance in Syria currently reaches 16.7 million, more than at any time since the outbreak of the Syrian civil war in 2011.

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According to a report by Russian Satellite News Agency on March 19, Russian President Vladimir Putin said that staff of The Russian Federation Security Service thwarted attempts to interfere in Russia’s internal affairs, including during the Russian presidential election.

Reported that Putin spoke at an expanded meeting of heads of the Russian Federal Security Service and said: You have paid special attention to completing tasks related to special military operations, reliably defended the constitutional order, and thwarted attempts to interfere in my country’s internal affairs, including during the recent election process.

Putin urged the Russian Federal Security Service to step up counter-terrorism operations, warning that Russia was dealing with a powerful opponent.

Putin instructed that the responsibility of the Russian Federal Security Service is to safeguard constitutional order and must resolutely stop attempts to incite trouble.

Reports said that Putin instructed the Russian Federal Security Service to investigate and deal with traitors without limitation.

Putin asked the Russian Federal Security Service not to forget the traitors who participated in the reconnaissance and sabotage team, to name and track them down, and punish them without time limit.

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Beijing, March 18: South Korea’s Deputy Minister of Health and Welfare Park Min-soo accused medical university professors of preparing to resign collectively as coercion on the 17th, and reiterated that the government will not give in to the expansion plan of medical universities.

The South Korean government announced an expansion plan for medical universities in early February, which was strongly opposed by the medical community. Nearly 10,000 interns and residents submitted their resignations and went on strike, causing confusion in diagnosis and treatment. Medical university students also collectively applied for suspension of school in protest. The Emergency Response Committee for Professors of the National Medical College of Korea announced on the 15th that professors from 16 university medical schools will collectively resign on the 25th of this month.

On October 18, 2023, tourists visited Gwanghwamun, Seoul, South Korea. Photo by reporter Wang Yiliang

Park Min-soo said in a speech on Yonhap News Agency TV on the 17th that the government will never adjust the plan to expand enrollment by 2000 people. The collective resignation of medical university professors is a threat to the public, and collective protests in the medical community must be stopped. Professors ‘claim that if students are at a disadvantage, they will not sit idly by is a challenge to the law.

Chu Young-soo, president of the National Central Medical Hospital of South Korea, said at a press conference that the medical university professor planned to resign in protest, threatening the patient’s health and even life. It is really desperate that a medical professor with an important position in the medical world should say such a thing.

Chu Young-soo also apologized for the hospital’s doctors ‘previous statement in support of the strike, saying that the statement did not represent the position of the National Central Medical Center, and urged the striking doctors to return to work as soon as possible.

As aging intensifies, Korean society will have an increasing demand for medical resources. According to estimates by the South Korean health department, if the current enrollment scale is maintained, the shortage of doctors in South Korea will reach 150,000 by 2035.

South Korean people generally welcome the medical university’s expansion plan. The medical community expressed opposition. They believed that the government’s expansion plan would address the symptoms rather than the root cause, and would not solve the problems of shortage of medical personnel and uneven resource allocation. Moreover, blind expansion of enrollment may lead to excessive medical care, thereby increasing the financial burden on the medical insurance system, and may also reduce the quality of teaching in medical schools. Critics say some in the medical profession are actually worried that expansion will lead to a reduction in their income. (Li Yannan)

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According to a report by the Tass news agency on July 17, Alexei Polisyuk, Director of the Second Department of CIS Affairs of the Russian Ministry of Foreign Affairs, told the Tass news agency that the United States has authorized Ukraine President Zelensky to launch a new strike on Russian territory.

Polisiuk pointed out: Washington is still fueling the escalation of the situation. They tried to justify their crimes while defending Kiev. Not only that, the Zelensky regime was also granted full powers to use American weapons to carry out new strikes on Russian territory.

He emphasized that the United States is still indulging in the dream of its own superior position, hoping that if Russia suffers strategic failure, it can safely hide across the ocean. He warned: Few among the American elite are aware of the risks of such arrogant and underestimating opponents ‘self-deception. For the United States and the world, the consequences may be unpredictable.

Polisiuk emphasized that behind the missile attack on Sevastopol, there was no doubt that U.S. military experts were providing various support services. They used the Pentagon’s drones circling over the area to target targets. (Russia) has made the most solemn representations to the U.S. ambassador to Moscow and the U.S. authorities in this regard, sending the clearest signal that terrorist attacks will lead to inevitable retaliation. As for the safety of the Crimean Peninsula and local residents, this is an absolute priority, and (Russia) is doing its best to provide reliable security. (Compiled by Tong Shiqun)

　　Amino acid chain is the main and core component in protein, but it is not necessarily the only component. Some protein may include some atoms or small molecules, whose function may be to perform protein function and/or increase its stability. Chemically, these cofactor are diverse, which may be organic molecules or metal elements. Some of them are briefly combined with protein chain, while others are closely combined with protein chain (sometimes even by covalent bonds) and become an integral part of the whole protein. The former is called coenzyme coenzyme, while the latter is called prosthetic group. Most coenzymes are small organic molecules from vitamins. For example, the common coenzymes NADH and FADH2. These two molecules from vitamin B complex, the former from nicotinic acid (vitamin B3) and the latter from riboflavin (vitamin B2), play the role of high-energy electron acceptor/donor in redox reaction.In some cases, Antibody Phage Display Service The advantages will become more and more obvious, and it will be able to develop indomitable after market tests. https://www.alphalifetech.com/

　　Some enzymes use several different cofactors, such as Pyruvate dehydrogenase (PDH), which is a key enzyme in the catabolism of sugar. The catabolism of sugar begins with glycolysis, which is a biochemical reaction pathway with 10 steps, transforming one glucose molecule into two pyruvate molecules, and then carrying out the citric acid cycle of tricarboxylic acid, which further decomposes pyruvate and oxidizes it into CO2. Pyruvate dehydrogenase PDH works at the intermediate junction of the above two reaction pathways (namely glycolysis and triacid cycle), and is responsible for activating pyruvate and enabling it to enter the tricarboxylic acid cycle. Specifically, PDH catalyzes the oxidative dearboxylation of pyruvate and forms acetyl coenzyme A (ACoA), which is the activated form of pyruvate. PDH is not a single enzyme but a complex composed of three components, each of which participates in a different step of pyruvate activation and uses different coenzymes. The first component uses thiamine pyrophosphate (TPP), which is a derivative of thiamine (vitamin B1). TPP allows the first component of PDH to be oxidized and decarboxylated at the same time, thus transforming pyruvate into acetyl, and the remaining carbon is discharged as CO2. The importance of TPP will be reflected in its absence. In fact, if people can’t get enough thiamine from food, they will get beriberi, which will damage several major systems of the human body.

　　The second component in PDH uses lipoic acid. It is an auxiliary group covalently bound to PDH. The active part of lipoic acid is a cyclic structure, which contains two covalently bonded sulfur atoms (that is, S-S bonds) (Figure 2.2c). This active part catalyzes the transfer of acetyl to coenzyme coenzyme A(CoA), the third cofactor of PDH. CoA is pantothenic acid, also known as the derivative of calcium pantothenate. The combination of acetyl and pantothenic acid involves the reduction of S-S bond, and its cyclic structure will open and form two sulfhydryl groups (one SH), one of which will bind acetyl. Sulfhydryl group is easy to react chemically, which can be reflected in the fact that sulfhydryl group is easily influenced by arsenic, a toxic derivative of arsenic. To sum up, the formation of acetyl coenzyme A involves the reduction of S-S bond of pantothenic acid cyclic structure. In order to keep PDH active, these two sulfur groups must be re-oxidized to restore the S-S bond.

　　Summer dusk, I sit with an old Chinese medicine in the breeze slowly chatting the river. Suddenly, the old man stared at my face for a moment and did not say anything. I was his heart to see some hair, asked: “The elderly, you are so concerned about my face, is not something to see ah?Sufficient data show that pu-erh tea It can drive many people to find jobs, thus driving economic development.

　　Old man smiled and said: “I am from primary school medicine, the teacher told me again and again, ‘people peace of mind level, see the eyes; life span, look at the face’ medical life, develop habits, and Oh, and people Together, they always want to look at his face more glances.

　　I said: “The elderly, all know that the eyes are the soul of the window, the first sentence I can understand, you can say ‘life span, look at the face’, I am a little puzzled.Human life, how to write in the face What about it? “

　　If a person is always sad intestine knot, mood melancholy, over-thinking, suspicious of the old man said: \ look at the face, in fact, I look at his face two, one eyebrow, Indecisive, can not see the hope of life and the good life, then, between the eyebrow must form a deep ‘eight’ pattern.’8 ‘pattern, is caused by squeezing distortion, Yin is too strong, the mood Difficult to cool, it will stagnate in the organs; Jiuyin poisonous, viscera unbearable corrosion, must be made for the disease; sick in the body, is bound to further deteriorate the mood.People once caught in the heart and the destruction of each other malignant disease Circle among the health does not exist, where there will be longevity of the reason? Eyebrow between the ‘eight’ pattern, in fact, cut the knife of life, so my teacher had more than once said to me, ‘brow wrinkled, You must be careful yo. “

　　The elderly, then let my heart anxious, usually not pay attention to the eyebrow between the ‘eight’ pattern, even with such a large knowledge. I could not help but curiosity driven, and then asked: “That mouth can see what?

　　A person if the hearty and fun, often laughing more than, the teeth often in the sun, then, in order to make the mouth a little bit, The ‘brackets’ is radian, as if the relative out of the two and a half months, set in the cheek on top of the vivid expression of light from the formation of the reasons we can see, brackets who are really comfortable Because the ‘brackets’ on both sides of the mouth, but also a symbol of the balance of yin and yang, therefore, it is encompassed by the health of the body, the spirit of the sparse, the vitality of life, leisurely and carefree, The music of the state of mind and the endless hope of life in such a life and mental state of the people, you say he can not live longer?

　　Really listen to Jun words, read the book a decade, my heart is not good fun ah. It turned out that our face, really reveal the mentality of our strengths and weaknesses, the vicissitudes of life and life status and other important information ah. Therefore, we usually still often look in the mirror to see if his face is increasing or deepening: the eyebrow between the “eight” pattern, or the mouth “brackets” it!

　　Organic chemistry is an important branch of studying carbon compounds, involving the source, structure, properties and other aspects of organic matter, and providing revelation for the material basis of life phenomena. It plays a key role in medicine, industrial production and other fields, but it still faces challenges such as green synthesis and drug molecular selectivity. Organic chemists are constantly exploring new reaction mechanisms and synthetic methods to promote the development of the discipline.At first, small molecules It developed out of control and gradually opened up a sky of its own. https://www.all-chemistry.com/

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　　In the vast universe of science, organic chemistry is like a bright star, leading us to explore the mystery of life. As a subject of studying carbon compounds, organic chemistry, with its unique charm, closely links all fields of natural science and reveals the material basis of life phenomena for us. Organic chemistry, an important branch of chemistry, is a subject that studies the source, structure, properties, separation, preparation, application and related theories of organic matter. “Organic matter” here refers to compounds containing carbon elements, such as alcohols, aldehydes, carboxylic acids, etc. It is worth noting that although organic matter mainly comes from organisms, with the development of science and technology, people have been able to synthesize many artificial organic compounds with biological activity, such as drugs, dyes, plastics and so on.

　　The main research contents of organic chemistry include: synthetic chemistry of organic matter; Metal organic chemistry and elemental organic chemistry; Physical and theoretical organic chemistry; Stereochemistry; Bioorganic chemistry; Natural product chemistry; Chemistry of organic materials.

　　The importance of organic chemistry:

　　1. Basis of life: From the origin of life to the growth and development of organisms, carbon always plays a vital role. Through the study of organic chemistry, we know the structure and function of biological macromolecules such as protein, nucleic acid, sugar and lipid, which are the material basis of life.

　　2. Key in the field of medicine: Many drugs and bioactive substances are organic compounds, such as antibiotics, antiviral drugs and hormones. By studying the structure and function of these substances, scientists are constantly discovering new treatments to protect human health.

　　3. The core of industrial production: Organic chemistry plays an important role in industrial production. For example, in the process of petroleum refining, heavy hydrocarbons in petroleum can be converted into light hydrocarbons by the action of catalysts; In the process of plastic synthesis, organic chemical reactions provide a steady stream of power for the plastic industry. Although organic chemistry has made remarkable achievements in many fields, it still faces many challenges.

　　First of all, in environmental protection, how to realize green synthesis and reduce the discharge of harmful waste is an urgent problem for organic chemists.

　　Secondly, in the field of medicine, how to improve the selectivity of drug molecules and reduce side effects is also a difficult problem to be solved urgently. Faced with these challenges, organic chemists are constantly exploring new reaction mechanisms, catalysts and synthetic methods. I believe that in the near future, organic chemistry will bring us more surprises and inject new vitality into the development of human society. Organic chemistry, as a discipline to study the molecular cornerstone of life, plays an important role in natural science. Let’s walk into this wonderful world hand in hand, grow in exploration, break through in innovation, and jointly write a bright future of organic chemistry.

　　Protein is composed of C (carbon), H (hydrogen), O (oxygen) and N (nitrogen). Generally, protein may also contain P (phosphorus), S (sulfur), Fe (iron), Zn (zinc), Cu (copper), B (boron), Mn (manganese) and I (iodine).We have every reason to believe. Antibody Discovery It will become the mainstream of the industry and will gradually affect more and more people. https://www.alphalifetech.com/

　　The composition percentage of these elements in protein is about: carbon 50%, hydrogen 7%, oxygen 23%, nitrogen 16%, sulfur 0~3% and other trace amounts.

　　(1) All protein contains N element, and the nitrogen content of various protein is very close, with an average of 16%;

　　(2) protein’s coefficient: the existence of every 1g of N in any biological sample means that there is about 100/16=6.25g of protein, and 6.25 is often called protein’s constant.

　　(3) protein is a biopolymer based on amino acids. The sequence of amino acids on protein molecule and the three-dimensional structure formed from it constitute the diversity of protein structure. Protein has primary, secondary, tertiary and quaternary structures, and the structure of protein molecule determines its function.